Ukuzama Ukuvimbela Ukuthola Isisindo kuma-anti-depressants

Ezweni elihle, iziguli ezinesifo sokudangala zinokukhetha ukwelashwa zombili ngemithi nange-psychotherapy. Ochwepheshe abahlukahlukene bezempilo yengqondo bangase balethe lezi zindlela zokwelapha ezimbili — ngokwesibonelo, udokotela wezifo zengqondo ophethe izidakamizwa noma isazi sokusebenza kwengqondo, usonhlalonhle, noma umhlengikazi wezifo zengqondo.

Inzuzo yokuhlanganisa lokhu kungenelela okubili ayisekelwe nje ekucabangeni ukuthi okuningi kungcono kunokuncane, kepha ekuhlaziyweni kwezifundo eziningi eziqhathanise imiphumela yokwelashwa okukodwa kuyo yomibili imiphumela yesikhathi esifushane neyesikhathi eside. Ekubuyekezweni okubanzi kwezifundo ezinje ezingama-52 ezelapha iziguli ezingaphezu kwe-3600 ezinenkinga yokudangala noma yokukhathazeka, ubufakazi babuningi ngokwedlulele ngokuhlanganisa izidakamizwa nokwelashwa kwengqondo. Kokubili ukwelashwa kunikela ngokulingana nomphumela, futhi akuncikile kolunye.

Kodwa-ke iziguli nodokotela abahlale ezweni elihle, futhi njengoba lokhu kubuyekezwa kusikisela, ukwelashwa okuhlanganisiwe akusetshenziswanga ngokwanele emisebenzini yamanje yomtholampilo. Ubhadane mhlawumbe lwenza kube nzima kakhulu ezigulini nakodokotela ukuthi baxhumane mathupha. I-athikili kuhlelo luka-Agasti lweNew England Journal of Medicine ikhuluma ngokwanda kwamacala ezifo zokugula ngengqondo, namasu okuhlola nokwelashwa angadingi ukuvakashelwa emahhovisi. Siyethemba, ezinye (eziningi?) Izinyanga kusukela manje, uhlelo lokunakekelwa kwezempilo kwengqondo luzokwazi ukubuyela ezimeni zangaphambi kweCovid, futhi ekugcineni luqhubekele ekunikezeni ukunakekelwa okuhlanganisiwe okunconyiwe.

Kepha iziguli kungenzeka ukuthi azilutholi lonke usizo eziludingayo, noma ngabe ukwelashwa kwengqondo kufakwa ekwelashweni kwezidakamizwa. Ukuzuza kwesisindo kungumphumela oseceleni wokwelashwa ngama-anti-depressants nemithi ehlobene nawo futhi kungaqala emasontweni ambalwa okuqala okwelashwa. Ingozi yokuthola isisindo ayilutho. Ekuhlolweni kwesimo sesisindo cishe kwabesilisa abayi-136,762 nabesifazane abayi-157,957 eminyakeni eminingana, uGafoor nabalingani bakhe bafuna ukunquma ukuthi ukusetshenziswa kwe-antidepressant kuhlotshaniswa nesisindo esengeziwe. Bathola isisindo esithe xaxa esitholwe phakathi kwamadoda angama-18,000 nabesifazane abangama-35,000 abaphathwa ngemithi yokulwa nengcindezi kunabantu abangalashwa. Ngaphezu kwalokho, isisindo saqhubeka nokuzuzwa isikhathi esiyiminyaka eyisishiyagalombili. Ababhali bakhathazeka ngezwi ngokunikela ngokusetshenziswa kwe-antidepressant ekusakazeni kokukhuluphala. Ngaphezu kwalokho, ukuzuza kwesisindo kungadala ezinye iziguli ukuthi ziyeke ukwelashwa ngaphambi kwesikhathi, noma zigweme ukubuyela emithini esikhathini esizayo uma ukucindezeleka noma ukukhathazeka kuvuselela isidingo sokwelashwa. Iziguli ezinesisindo esivamile ngaphambi kokwelashwa ziyaxakaniseka futhi azijabule lapho zizithola zisezigabeni zokhuluphele noma ezikhuluphele. Bangase babhekane nesimo sengqondo esinamahloni sabanye, futhi bangakuthola kunzima ukuchaza ukuthi ukuzuza kwabo kwesisindo bekungumphumela wecala lomuthi wabo ngisho naseqenjini lokusekelwa lokwehlisa isisindo. Futhi kunobufakazi be-anecdotal bokuthi ukulahleka kwesisindo kungaba nzima ukufeza amasonto noma ngisho nezinyanga ngemuva kokuphela kokwelashwa kwengcindezi.

Ingabe kwanele ukwenziwa ukuvimbela noma ukunciphisa ukuzuza kwesisindo njengomphumela oseceleni wezidakamizwa? Ngabe ukungenelela kuqalwe ngaphambi kwesikhathi ngokwanele kumaseshini okwelashwa ngaphambi kokutholwa okungaphezu kwephawundi noma isisindo esingamabili? Noma ingabe udaba luyashaywa indiva ukuvimbela isiguli ekwenqabeni ukwelashwa kwemithi uma lo mphumela wecala ubaziwa? Ngabe ukubonisana nodokotela wezokudla kufanele kufakwe njengengxenye yephakeji lokwelashwa futhi uma kunjalo, yiluphi uhlobo lokungenelela kokudla olungaphumelela?

Okungenani, isiguli kufanele saziswe ngokutholakala kwesisindo njengomphumela ohlangothini futhi sicelwe ukuthi sazi noma yiluphi ushintsho ekuthandeni ukudla okulula, ikakhulukazi lezo ezine-carbohydrate eningi, kanye nokwehla kokugcwala ngemuva kokudla. Lezi zinguquko zokudla kungenzeka zibe ubufakazi bokuthi ama-antidepressant (s) athinta ikhono le-serotonin lokulinganisa ukusutha. Ukwazi ukuthi le neurotransmitter iyabandakanyeka ekunqanyulweni kokudla kuholele ekwakhiweni kwezidakamizwa zokwehlisa isisindo. Kwakucatshangwa ukuthi ukwenza i-dieter igcwale ngandlela thile ngaphambi kokudla kungahle kudle ukudla okuncane. Ngeshwa, imininingwane engaphansi kakhulu iyatholakala mayelana nokuthi i-antidepressants ivimbela kanjani lo msebenzi we-serotonin futhi ibangele ukudla ngokweqile nokuzuza kwesisindo. Impela, mhlawumbe ukungabikho kokwelulekwa ngokuthi ungawunqanda kanjani lo mphumela we-anti-depressant kungenxa yokungazi ukuthi kanjani.

Eminyakeni eminingana edlule sanikezwa le nkinga lapho sisungula umtholampilo wokwehlisa isisindo esibhedlela iMcLean, isibhedlela sabagula ngengqondo esihambisana neHarvard. Amakhasimende ethu avela esibhedlela nasemphakathini athole isisindo ngenkathi edla izidakamizwa ezahlukahlukene zengqondo. Bonke babenenkinga yokulawula ukudla okulula, kanti abanye babedla kabili kulandelana ngoba babengazizwa besuthi. Ukunikeza izidakamizwa zokudla okwenyusa umsebenzi we-serotonin kwakungeyona inketho kepha okunye okwemvelo, okungeyona eyomuthi kwakuyikho. Njengoba ukuhlanganiswa kwe-serotonin nomsebenzi wenziwa ngokusetshenziswa kwe-carbohydrate sitshele amaklayenti ethu ukuthi adle inani elincane le-carbohydrate ngaphambi kwesidlo sasemini nesasebusuku. Besithemba ukuthi lokhu kungakhuphula ukuhlanganiswa kwe-serotonin ngokwanele ukukhiqiza umuzwa wokusutha ngaphambi kokudla. Uhlelo lokudla olulawulwa amakhalori, ukuzivocavoca nokwelulekwa lufakiwe phakathi kohlelo lokwehlisa isisindo. Kuyathakazelisa ukuthi iningi lamakhasimende ethu belingakaze libe nenkinga yesisindo ngaphambi kokuya emithini yabo, futhi lapho sebengasakuzwanga ukungasuthi, ukulandela ukudla okunempilo nokuzivocavoca akubonakali kunzima.

Okunye ukungenelela kokudla kungasebenza futhi kufanele kuvivinywe. Kodwa ukwenza lutho ukulawula ukuzuza kwesisindo akufanele kube inketho. Njengoba uBen Franklin asho, "Isilinganiso esisodwa sokuvimbela sibiza ikhilogremu lekhambi."