Kungani Isifo Sika-Alzheimer Sithinta Abesifazane Abangaphezu Kwabesilisa?

Kukhona iqiniso elimangazayo, elaziwa kancane ngesifo i-Alzheimer's (AD), isifo se-neurodegenerative esithinta abantu baseMelika abalinganiselwa ezigidini ezi-5.8-sithinta ngokungalingani abesifazane. Ababili kwabathathu kulabo abatholakala benesifo i-Alzheimer e-U.S. Ngabesifazane, ngokusho kombiko wakamuva we-Alzheimer's Association. Ososayensi abazi ukuthi kungani.

I-Women’s Alzheimer’s Movement (WAM), engenzi nzuzo esungulwe nguMaria Shriver, ihamba phambili ekuthatheni izinyathelo ukusiza ukuthola izixazululo. UDkt Sanjay Gupta, intatheli yezokwelashwa e-Emmy Award ewinile i-CNN, ujoyine uShriver engqungqutheleni ye-WAM Research Awards Summit ebibanjwe ngoFebhuwari 11, 2021, ukuhlonipha labo abathola imali engu- $ 500,000 yokunikela ngemali yocwaningo lwesifo sabesifazane i-Alzheimer's.

Intatheli eyazuza umklomelo ka-Emmy, umbhali othengisa kakhulu, nowayengunkosikazi wokuqala waseCalifornia, uMaria Shriver uyakwazi ukubhujiswa kwe-Alzheimer's. Ubaba wakhe ongasekho, uSargent Shriver, watholakala enesifo i-Alzheimer's ngo-2003. Wasungula i-WAM ngenhloso yokuxhasa ucwaningo lwe-Alzheimer's olwenziwa ngabesifazane ezikhungweni ezihola phambili zezesayensi ezweni lonke, ukuze kubhekwane nezidingo ezithile zabesifazane, kubandakanya nabesifazane abanemibala , ukusiza ukunciphisa ubungozi besifo i-Alzheimer's.

"Kulo nyaka sigxile emandleni okucwaninga ukushintsha umzila wezempilo yobuchopho besifazane unomphela," kusho uShriver ku "The Future Brain" kwiPsychology Today.

UGupta uyi-neurosurgeon futhi ungumbhali wencwadi entsha Gcina Kucijile: Yakha Ubuchopho Obungcono Kunoma Yimuphi Ubudala lokho kunikeza ukuqonda kwesayensi mayelana nokuthi ungakhuphula futhi uvikele kanjani ukusebenza kobuchopho nokugcina impilo yokuqonda. Ngenkathi esemusha, umkhulu wakhe amthandayo waqala waba nesifo i-Alzheimer's, esasikhwezela intshisekelo yakhe yesikhathi eside yokuqonda ubuchopho, nokufundisa abanye ngalesi sifo nokuthi yini engenziwa ngaso.

"Umsebenzi wami ugxile kakhulu ekwakheni izixazululo zabantu zokufeza ukusebenza kwengqondo okuqonda kahle," kuchaza uGupta ku "The Future Brain" kwiPsychology Today. "Kodwa-ke, kubalulekile ukuqaphela ukuthi ucwaningo lwezokwelapha olungokomlando luzibukile izingqondo zabesifazane nezingozi zabesifazane ezihlukile ekuthuthukiseni izifo zokucabanga. Izibonelelo zocwaningo lwe-WAM ezinikezwe ososayensi nodokotela abaphezulu kwezempilo yobuchopho nokuvimbela i-Alzheimer zinamandla okuguqula leli qiniso ebuchosheni besifazane. ”

Abaxhasi bahlanganisa ososayensi abavela kulo lonke elase-United States emkhakheni wokucwaninga ukuthi kungani isifo i-Alzheimer sithinta abesifazane ngokungalingani.

ULisa Mosconi, Ph.D., e-Women's Brain Health Initiative e-Weill Cornell eNew York, uzosebenzisa isibonelelo sakhe ukuphenya ukuthi yiziphi ezinye izinto zokuzala (ukulawulwa kokuzalwa, inani lokukhulelwa, ukusetshenziswa kwe-hormone therapy, ubudala lapho esesikhathini, iminyaka yobudala ukunqamuka kokuya esikhathini) kudlala indima ekuqaleni nasekuqhubekeni kwe-Alzheimer's kwabesifazane. Lokhu kwakhela phezu kwesisekelo somsebenzi wakhe ku-estrogen kanye nokunqamuka kokuya esikhathini njengezinto ezinobungozi be-Alzheimer's.

ULaura Cox, Ph.D., e-Ann Romney Center for Neurological Diseases eBrigham naseWomen Hospital eBoston, uzosebenzisa isibonelelo sakhe ukuqonda ukuthi i-gut microbiota ilawula kanjani i-Alzheimer ngokulinganisa i-epigenetics emadodeni nakwabesifazane ukuze bathole izindlela ukwelapha kangcono i-AD kwabesifazane.

URoberta Diaz Brinton, Ph.D., e-University of Arizona Center for Innovation in Brain Science, usebenzisa isibonelelo sakhe ukucwaninga izindlela zokwelapha isifo sikashukela sohlobo lwe-2 kanye nezingozi ezihambisana ne-Alzheimer's kwabesifazane.

UDean Ornish, MD, e-Preventative Medicine Research Institute eSan Francisco, wanikezwa isibonelelo sokuqhubeka nomsebenzi wakhe wokuphayona ekuguquleni isifo senhliziyo ngokushintsha kwendlela yokuphila ngesilingo esilawulwa ngokungahleliwe ukubona ukuthi ukuqhubeka kwe-Alzheimer's early kungaguqulwa ngendlela yokuphila umuthi.

URichard Isaacson, MD, e-Alzheimer's Prevention Clinic e-Weill Cornell eNew York, uzosebenzisa imali ukuthola ulwazi kubantu besifazane bezinhlanga ngokuqonda kwabo isifo i-Alzheimer kanye nezingozi ukuze kwakheke umhlahlandlela wezemfundo ohlose abesifazane abavela ezizindeni ezahlukahlukene ukusebenzisana noDkt. Eseoasa Ighodaro waseMayo Clinic eRochester, uDkt Josefina Melenze-Cabrero eSan Juan, ePuerto Rico, uDkt Amanda Smith e-University of Southern Florida Alzheimer's Institute, kanye noDkt Juan Melendez eJersey, eNgilandi.

Uxhaso lwemali yesibonelelo lubandakanya nabososayensi besifazane abasebenzisana ne-Alzheimer's Association umsebenzi wabo owaphazanyiswa ubhadane lwe-COVID-19 lomhlaba jikelele. UMegan Zuelsdorff, Ph.D., ufunda izingcindezi nemvelo yezenhlalo njengezinto ezingaba yingozi;

U-Ashley Sanderlin, Ph.D., uphenya ukudla kwe-ketogenic nokulala; UFayron Epps, Ph.D., uphenya indima yokholo nokunakekela emphakathini wase-Afrika waseMelika; noKendra Ray, Ph.D., ucwaninga ngokwelashwa komculo nokunakekelwa.

“Ngokomlando ucwaningo lwezokwelapha lushiye abesifazane ngaphandle kwezilingo zokwelashwa kanye nezifundo ezinkulu zobuchopho, okunomphumela omubi wokuthi kukhona igebe lolwazi ngempilo yabesifazane nokuthi kungani besengozini enkulu yokuhlaselwa i-Alzheimer's, ukuwohloka komqondo, nezinye izifo ezinengqondo. , ”Kusho uShriver. "Ukuxhasa lezi zifundo ze-Alzheimer's ezenzelwe abesifazane kusiza ukuvala lelo gebe. I-WAM ikholelwa ngokuqinile emandleni okucwaninga, nokuthi kuphela ngokusekela isayensi lapho sizokwenza khona izindlela ezingagcina ziholele emthonjeni wokugoma, ekwelashweni noma ekwelashweni."

Imininingwane © 2021 Cami Rosso. Wonke Amalungelo Agodliwe.